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Metformin
Metformin

Metformin

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$75.00 USD
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Why choose us ?

01

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Experienced healthcare providers committed to your well-being.

02

No insurance needed

Upfront pricing, with no hidden fees.

03

Ongoing medical support

Ongoing assistance with your specific health condition

What is Metformin?

Metforminis a well-known oral medication traditionally used to manage type 2 diabetes. In recent years, it has gained recognition inlongevity and anti-aging medicinedue to its impact oninsulin sensitivity, mitochondrial health, inflammation, and cellular aging. As acaloric restriction mimetic, Metformin is now widely used off-label to supportmetabolic health, fat loss, and cellular resilience, with potential to reduce age-related diseases and improve health span.

Benefits:

✔ Enhances insulin sensitivity and stabilizes blood sugar
✔ May reduce visceral fat and improve body composition
✔ Supports mitochondrial function and metabolic flexibility
✔ May reduce the risk of age-related diseases (heart disease, cancer, cognitive decline)
✔ Activates cellular repair pathways (AMPK, autophagy)

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How does it work?

Metformin targets multiple aging-related pathways through metabolic regulation and mitochondrial support:

  1. AMPK Activation
    • Metformin activates AMP-activated protein kinase (AMPK), a key energy sensor that promotes fat oxidation, glucose uptake, and mitochondrial biogenesis—mimicking the effects of fasting.
  2. Insulin Sensitivity & Glycemic Control
    • It lowers circulating insulin and glucose levels, helping reduce systemic inflammation and oxidative stress, two hallmarks of aging and metabolic decline.
  3. mTOR Pathway Modulation
    • By inhibiting the mTOR pathway, Metformin slows down cellular overgrowth and supports autophagy—a crucial anti-aging process for cellular cleanup and repair.
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How it works:

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Take the health questionnaire

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Step - 2

Get your prescription

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Step - 3

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Frequently Asked Questions
What can I expect with Metformin treatment?

• Start with500mg once daily, gradually titrate up to 1000–2000mg daily if tolerated

•Week 1–2:Improved blood sugar and appetite control

•Week 4+:Enhanced energy, fat loss, cognitive clarity

• Full anti-aging and metabolic benefits seen with consistent, long-term use

• Best when combined with fasting, low-glycemic nutrition, and exercise

• Missed dose? Skip and resume at the next scheduled time—do not double up
What are the possible side effects of Metformin?

Common (Typically transient):
• Nausea
• Diarrhea
• Gas or bloating
• Metallic taste

Less Common / Monitor If Present:
• Vitamin B12 deficiency (check annually)
• Lactic acidosis (rare; risk higher in kidney/liver impairment or alcohol abuse)
• Decreased appetite or mild fatigue

Precautions:

  • Not recommended in patients with eGFR <30 mL/min
  • Caution with alcohol or severe calorie restriction
  • Monitor B12 annually with long-term use
  • Take with food to reduce GI side effects